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Clinical Trials - Diseases by specialty group


Bone Marrow Transplant and Cellular Therapy 17

    Protocol ID
  • Associated disease
    Title
    Evaluation of Long-term Safety in Paediatric Patients With B-precursor Acute Lymphoblastic Leukemia (ALL) who Have Been Treated With Either Blinatumomab or Chemotherapy, Followed by Transplantation
    BMTCTN-1904
  • Bone Marrow Transplant and Cellular Therapy
    BMTCTN-1904 Hematopoietic Cell Transplantation Using Treosulfan-Based Conditioning for the Treatment of Bone Marrow Failure Diseases
    Matched Unrelated Donor and Partially Matched Related Donor Peripheral Stem Cell Transplantation with Alpha/Beta T-Cell and B-Cell Depletion for Patients with Hematologic Malignancies with Targeted ATG Dosing Pilot Study, IDE 13641
    Communication in the Early Pediatric Cancer Treatment Period
    IIT-Steineck-CARTPLUS: Chimeric Antigen Receptor T-cell Pediatrics Living with Uncertainty (CAR T-PLUS) Intervention Proof of Concept Study
    Phase 1 Study of Redirected Autologous T Cells Engineered to Contain an Anti-CD19 and Anti-CD20 scFv Coupled to CD3 and 4-1BB Signaling Domains in Patients with Relapsed and/or Refractory CD19 or CD20 B-Cell Acute Lymphoblastic Leukemia
    Serial Response and Biomarker-Guided Steroid Taper for Children with GVHD
    A multicenter safety study of unlicensed, investigational cryopreserved cord blood units (CBUs) manufactured by the National Cord Blood Program (NCBP) and provided for unrelated hematopoietic stem cell transplantation of pediatric and adult patients
    NMDP-10-CBA
  • Bone Marrow Transplant and Cellular Therapy
    A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) for transplantation in pediatric and adult patients with hematologic malignancies and other indications
    A Phase 1/2 Multi-Center Trial of Vorinistat for Graft vs Host Disease Prevention in Children, Adolescents, and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation
    NYMC-571
  • Bone Marrow Transplant and Cellular Therapy
    The Safety and Efficacy of Prophylactic Defibrotide Administration in Children, Adolescents, and Young Adults with Sickle Cell Disease or Beta Thalassemia Following Myeloablative Conditioning (MAC) and Haploidentical Stem Cell Transplantation Utilizing CD34 Enrichment and T-Cell (CD3) Addback (IND 127812)
    NYMC-579
  • Bone Marrow Transplant and Cellular Therapy
    A Pilot Study in the Treatment of Refractory Adenovirus (AdV) Infection with Related Donor AdV Cytotoxic T-Lymphocytes (AdV-CTLs) in Children, Adolescents and Young Adult Recipients
    NYMC-580
  • Bone Marrow Transplant and Cellular Therapy
    A Pilot Study in the Treatment of Refractory Cytomegalovirus (CMV) Infections with Related Donor CMV Specific Cytotoxic T-Cells (CTLs) in Children, Adolescents and Young Adult Recipients
    NYMC-581
  • Bone Marrow Transplant and Cellular Therapy
    A Pilot Study in the Treatment of Refractory Epstein-Barr Virus (EBV) Infection with Related Donor EBV Cytotoxic T-Lymphocytes in Children, Adolescents and Young Adult Recipients
    The Role of KIR-Favorably Mismatched Haploidentical Transplantation and KIR-Polymorphisms in Determining Outcomes of Children with ALL/AML/MDS Undergoing Allogeneic Hematopoietic Cell Transplantation
    PTCTC-EXCEL
  • Bone Marrow Transplant and Cellular Therapy
    A Phase II Pilot Study of Donor-Derived Ex-Vivo Expanded Natural Killer Cell Infusions in Children and Young Adults with High-Risk Acute Myeloid Leukemia Receiving Myeloablative HLA-Haploidentical Hematopoietic Cell Transplant: A Multicenter Pediatric Transplantation and Cellular Therapy Consortium (PTCTC) Study (EXCEL Trial)
    A Phase II Pilot Trial to Estimate Survival After a Non-Total Body Irradiation (TBI) Based Conditioning Regimen in Patients Diagnosed with B-Acute Lymphoblastic Leukemia (ALL) Who Are Pre-Allogeneic Hematopoietic Cell Transplantation (HCT) Next-Generation-Sequence (NGS) Minimal Residual Disease (MRD) Negative
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Michael Burke, MD

"The steady improvement in survival for children with cancer is a direct result of their enrollment onto clinical trials; without which we would remain decades behind in terms of scientific advances in pediatric cancer." ~Michael J. Burke, MD